The Clinical Investgation of Different Doses of Atorvastatin in Unstable Angina Pectoris

Abstract：Objective:To investigate the influence of different doses of atorvastatin in the prognosis of unstable angina.Methods:80 cases of patients treated with unstable angina were randomly divided into two groups.In the control groups,40 patients accepted conventional treatments and Atorvastatin 20 mg daily,while in the treatment groups 40 patients accepted conventional treatment and Atorvastatin 40 mg daily.Both groups were measured before and after 180d treatment at the four lipids,CRP,and were observed of Re-angina,myocardial infarction and cardiac death and other undesirable occurrence of cardiovascular events.Results:The lipid levels of two groups had varying degrees of reduction after treatment.Compared with the control group,the observation group was more obvious(P<0.05).The two groups both reduce CRP level after treatment.Compared with the control group,the effect of the observation group was more obvious(P<0.05).With the occurrence of adverse events,the diffierence was not statistically significant between two groups(P>0.05).Conclusion:Atorvastatin intensive treatment can improve the prognosis of patients with unstable angina and intensive treatment after weigh in patients with drug use pros and cons,recommended 40 mg/d.