Observation on the Efficacy of Early Debridement Combined with Vacuum Sealing Drainage in Patients with Perineal Necrotizing Fasciitis after Trauma
CHEN Zhigang
JIANG Long
LIN Pingyue
WANG Dingqian
JI Xiaojian
Abstract：Objective To investigate the clinical value of early radical debridement combined with vacuum seal-ing drainage(VSD)versus traditional open dressing change in the treatment of perineal necrotizing fasciitis(PNF)after trauma.Methods A retrospective study was conducted,including 60 patients with post-traumatic PNF admitted be-tween January 2018 and July 2024.According to the actual surgical protocol,patients were divided into an observation group(early radical debridement+VSD,n=30)and a control group(conventional debridement+traditional open dressing change,n=30).The clinical efficacy,levels of inflammatory factors[white blood cell count(WBC),C-reactive protein(CRP),interleukin-6(IL-6)],pain level[Visual Analogue Scale(VAS)],and recovery indicators(necrosis sloughing time,wound healing time,hospital stay)were compared between the two groups.Results The total clinical effective rate in the ob-servation group was significantly higher than that in the control group(96.67%vs.80.00%,P=0.044).On postoperative day 7,the levels of WBC,CRP,and IL-6 in the observation group were significantly lower than those in the control group(P<0.001).On postoperative days 1,3,and 7,the VAS scores in the observation group were significantly lower than those in the control group(P<0.05).The necrosis sloughing time,wound healing time,and hospital stay in the observation group were significantly shorter than those in the control group(P<0.001).Conclusion For patients with post-traumatic PNF,the application of early radical debridement combined with VSD can more effectively enhance clinical effica-cy,alleviate systemic inflammatory response and post-operative pain,accelerate wound healing,and shorten hospital stay.Its comprehensive effect is superior to traditional open dressing change.
Keywords：perineal necrotizing fasciitisvacuum sealing drainagedebridementinfection controlpain
Publication Date：2025-11-28
Online Publishing Date：2026-03-05(First online date of this platform, not the publication date of the document)
Pages：5( 1326-1330 )