Effect Analysis of Prehospital Emergency Care Optimization on Thrombolytic Therapy Process and Prognosis in Patients with Acute Cerebral Infarction

MIN Yukai; WU Bing; DENG Longhua; WU Xiaowei

doi:10.13919/j.issn.2095-6274.ZHJY202510048

Abstract：Objective To investigate the impact of pre-hospital emergency care on the treatment outcomes of pa-tients with cerebral infarction.Methods A retrospective analysis was conducted on the clinical data of 120 cerebral infarction patients admitted to the Xiamen Medical Emergency Center from January 2021 to December 2024.Based on whether pre-hospital emergency care was implemented,patients were divided into an observation group(received pre-hos-pital emergency care and were transported to the hospital by ambulance,n=60)and a control group(transported to the hospital by family members,n=60).Neurological function,activities of daily living(ADL),thrombolytic therapy-related indicators,and complication incidence were compared between the two groups.Results Before treatment,there was no significant difference in NIHSS scores between the two groups(P>0.05).After treatment,NIHSS scores significantly decreased in both groups(P<0.001),with a more pronounced decrease in the observation group(P<0.001).Before treat-ment,there was no significant difference in Barthel Index between the two groups(P>0.05).After treatment,the Barthel Index significantly increased in both groups(P<0.001),with a more pronounced increase in the observation group(P<0.001).Compared to the control group,the door-to-needle time(DNT)was significantly shorter in the observation group(P<0.001),the proportion of DNT≤60 min was significantly higher(P<0.05),and the mortality rate was significantly lower(P<0.05).The complication incidence rate was 13.33%(8/60)in the observation group,significantly lower than 33.33%(20/60)in the control group(P<0.05).Conclusion Timely and effective pre-hos-pital emergency care can effectively improve neurological function and activities of daily living in cerebral infarction pa-tients,shorten DNT,and reduce the risk of mortality and complications.