Application of an Integrated Rescue Model in Acute ST-Sgment Elevation Myocardial Infarction

LI Zeding; DU Zhichao; CHEN Tianxi

doi:10.13919/j.issn.2095-6274.ZHJY2025

Abstract：Objective To investigate the effect of an integrated rescue model in the treatment of patients with acute ST-segment elevation myocardial infarction(STEMI).Methods A total of 98 acute STEMI patients admitted to Guihang Guiyang Hospital from January 2024 to December 2024 were selected as the study subjects.According to a com-puter-generated random sequence,all patients were randomly divided into two groups:the study group(n=49,integrated rescue model)and the control group(n=49,conventional rescue model).The key rescue process time points and hospitali-zation duration,myocardial enzyme indicators,rescue efficacy,and the incidence of major adverse cardiac events(MACE)were compared between the two groups.Results Compared with the control group,the study group showed significant-ly shorter time intervals from symptom onset to first medical contact(S-to-FMC,P=0.001),from first medical contact to ECG completion(FMC-to-ECG,P<0.001),from ECG completion to balloon dilation(ECG-to-B,P<0.001),from door to balloon dilation(D-to-B,P<0.001),and hospitalization duration(P<0.001).Before treatment,there were no signif-icant differences in the levels of creatine kinase(CK,P=0.418)and creatine kinase isoenzyme MB(CK-MB,P=0.374)between the two groups.After treatment,the levels of CK and CK-MB decreased in both groups(P<0.001);furthermore,compared with the control group,the study group had significantly lower levels of CK and CK-MB(P<0.001).Com-pared with the control group,the study group had a significantly higher total effective rate of rescue(95.92%vs.81.63%,P=0.025)and a significantly lower incidence of MACE(12.24%vs.30.61%,P=0.027).Conclusion The integrated rescue model can significantly shorten the key rescue process time points and hospitalization duration in acute STEMI pa-tients,improve myocardial enzyme indicators,enhance rescue efficacy,and reduce the risk of major adverse cardiac events.