Observation on the Efficacy of Yishen Yangxue Decoction in Treating Renal Anemia in Uremic Patients Undergoing Hemodialysis
WEI Xiaowei
XU Hua
lIU Youmin
Qian Yanping
HUANG Xiaomei
Abstract：Objective To investigate the effect of Yishen Yangxue Decoction on uremic patients with renal anemia undergoing hemodialysis.Methods Ninety～two uremic patients with renal anemia receiving hemodialysis in Jiangle General Hospital from January 2023 to August 2024 were enrolled and randomly divided into two groups using a random number table.The control group(n=46)received recombinant human erythropoietin(rhEPO)thera-py,while the observation group(n=46)received Yishen Yangxue Decoction in addition to the control treatment.The therapeutic efficacy,blood parameters,erythropoietin resistance index(ERI),average weekly rhEPO dosage,renal function,quality of life,and adverse reactions were compared between the two groups.Results The total effective rate was significantly higher in the observation group than in the control group(93.48%vs.78.26%,P<0.05).After treatment,the observation group showed significantly better results than the control group in terms of hemoglobin(Hb),hematocrit(HCT),serum ferritin(SF),transferrin saturation(TSAT),and quality of life scores.Meanwhile,the eryth-ropoietin resistance index,weekly rhEPO dosage,serum creatinine(Scr),and blood urea nitrogen(BUN)levels were significantly lower in the observation group than in the control group(P<0.05).The incidence of adverse reactions was lower in the observation group than in the control group(4.35%vs.17.39%,P<0.05).Conclusion Yishen Yangxue Decoction can improve the anemia status and renal function,reduce erythropoietin resistance and the re-quired rhEPO dosage in uremic hemodialysis patients with renal anemia,with a high safety profile.
Keywords：UremiaHemodialysisRenal anemia
Publication Date：2025-09-28
Online Publishing Date：2026-01-27(First online date of this platform, not the publication date of the document)
Pages：5( 1024-1028 )