Efficacy Observation of Thrombolytic Injection Combined with Buyang Huanwu Decoction in the Treatment of Acute Cerebral Infarction

DENG Jing; LI Shundong

doi:10.13919/j.issn.2095-6274.ZHJY202412025

Abstract：Objective To investigate the clinical efficacy of intravenous thrombolytic therapy with Xue-fuzhuyu injection combined with Buyang Huawu Decoction in the treatment of acute cerebral infarction.Meth-ods This study employed a simple random sampling method to select 100 patients diagnosed with acute cerebral infarction from the People's Hospital of Jinhua County,Guizhou Province,from July 2022 to July 2024.Patients were randomly assigned to two groups using a random number table:the control group(n=50)received intravenous thrombolytic therapy with Xuefuzhuyu injection,while the observation group(n=50)received Xuefuzhuyu injection in conjunction with Buyang Huawu Decoction.Statistical analysis was performed to compare neurological func-tion,prognosis,activities of daily living,cerebral blood flow,clinical efficacy,collateral circulation grading,and incidence of adverse effects between the two groups.Results After treatment,the observation group exhibited significantly lower NIHSS and mRS scores compared to the control group(P<0.05).Additionally,the observation group demonstrated higher Barthel Index(BI)scores,peak systolic blood flow velocities in the anterior,middle,and posterior cerebral arteries,and a greater overall effective rate(P<0.05).The proportion of collateral circulation grading level 0 in the observation group was lower than that in the control group,while the proportions of levels 1 and 2 were higher(P<0.05).Conclusion The combination of intravenous thrombolytic therapy with Xuefuzhuyu injection and Buyang Huawu Decoction exhibits superior effectiveness in the treatment of acute cerebral infarction compared to Xuefuzhuyu injection alone.This combined approach significantly enhances cerebral blood flow,im-proves collateral circulation grading,benefits neurological function and prognosis,enhances patients'activities of daily living,and reduces the incidence of adverse ef-fects.