Study on the Efficacy of Emergency Digestive Endoscopy in the Treatment of Non-Variceal Upper Gastrointestinal Bleeding

HE Lu; LI Debin; HUANG Tengfei

doi:10.13919/j.issn.2095-6274.ZHJY202410035

Abstract：Objective To explore and analyze the clinical efficacy of emergency gastrointestinal endosco-py in the treatment of upper gastrointestinal bleeding(UGIB).Methods A total of 92 patients with UGIB who were treated at Lianjiang County General Hospital from August 2023 to August 2024 were selected for this study.Patients were divided into two groups based on their admission sequence:the study group(n=46),who received emergency endoscopic treatment,and the control group(n=46),who were treated with medication.The clinical recovery indicators,coagulation-related parameters,oxidative stress markers,clinical efficacy,and the incidence of adverse events were compared between the two groups.Results Compared with the control group,the study group showed significantly shorter times to control bleeding,restore bowel sounds,achieve complete hemostasis,and shorter hospital stays(P<0.001).The amount of blood transfusion was also significantly lower in the study group(P<0.001).Both groups showed recovery of fibrinogen levels to normal,but the increase in the study group was more significant(P<0.001).The study group also demonstrated more significant reductions in thrombin time,prothrombin time,activated partial thromboplastin time,as well as levels of antidiuretic hormone and malondial-dehyde,compared to the control group(P<0.001).The clinical overall efficacy rate was higher in the study group,and the total incidence of adverse events was lower(P<0.05).Conclusion Emergency gastrointestinal endosco-py for patients with UGIB can shorten clinical recovery time and hospital stay,improve coagulation and oxidative stress-related indicators,enhance hemostasis efficiency,and reduce the risk of adverse events.