Clinical Effect of Modified Radical Resection Versus Breast-conserving Surgery in the Treatment of Early-stage Breast Cancer and the Effects of Sleep Status
JIANG Yan
WU Xiuping
Abstract：Objective To analyze the clinical value of performing modified radical mastectomy versus breast-conserving surgery in patients with early-stage breast cancer. Methods A retrospective analysis was conducted on the clinical data of early-stage breast cancer patients treated at Zhangzhou Zhengxing Hospital from April 2020 to April 2022. Based on the surgical approach,patients were divided into a modified radical mastecto-my group (control group) and a breast-conserving surgery group (observation group),with 50 cases in each group. Surgical indicators,postoperative breast aesthetics,long-term prognosis,short-term complications,and sleep qual-ity were compared between the two groups. Results The postoperative blood loss in the observation group was significantly less than that in the control group (P<0.001). The surgery duration and total hospital stay in the ob-servation group were significantly shorter than those in the control group (P<0.001). One year postoperatively,the observation group had significantly higher scores in breast aesthetics,including smoothness,symmetry,skin appear-ance,skin color,incision scars,and nipple movement (P<0.001). There were no significant differences in survival rate (P=0.695),local recurrence rate (P=0.400),and distant metastasis rate (P=0.558) between the two groups. The observation group had 2 cases of short-term complications,significantly fewer than the 8 cases in the control group (P=0.046). Post-treatment,the observation group had significantly better sleep quality indicators,including sleep onset time,sleep duration,sleep quality,sleep efficiency,sleep disturbances,use of hypnotics,daytime dysfunction,and total PSQI score,compared to the control group (P<0.001). Conclusion For patients with early-stage breast cancer,both breast-conserving surgery and modified radical mastectomy effectively remove the tumor tissue. How-ever,breast-conserving surgery is more beneficial for postoperative recovery,maintaining the aesthetic appearance of the affected breast,ensuring higher safety,and improving postoperative sleep quality.
Keywords：breast cancerbreast-conserving surgerymodified radical mastectomyaesthetic appearancesleep quality
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1176-1179 )