Evaluation of the Effectiveness and Security of Nasal Continuous Positive Airway Pressure in the Therapy of Serious Pneumonia in Children

KE Qingbo

doi:10.13919/j.issn.2095-6274.ZHJY202409037

Abstract：Objective Exploring the clinical efficacy and safety of nasal continuous positive airway pressure ventilation in children with severe pneumonia. Methods A retrospective collection of clinical data was conduct-ed on 100 children with severe pneumonia admitted to Shishi Maternal and Child Health Hospital from January 2021 to January 2024. According to the different treatment plans adopted,they were divided into an observation group (nasal continuous positive airway pressure ventilation) and a control group (nasal cannula oxygen inhalation),with 50 children in each group. Compare the clinical efficacy,clinically relevant symptom relief time,blood gas re-lated indicators,vital sign related indicators,PCIS score,and safety between two groups of pediatric patients. Re-sults The total clinical effective rate of the observation group after treatment was significantly higher than that of the control group (P<0.05). The observation group had a shorter time for heart rate to return to normal,breathing difficulties to alleviate,and lung rales to disappear compared to the control group (P<0.001). Before treatment,there were no significant differences in the levels of PaO2,PaCO2,SaO2,respiratory rate,heart rate,and PCIS score between the two groups of children (P>0.05);After treatment,the levels of the above indicators in both groups of children improved,and the PaO2,SaO2 levels,and PCIS scores in the observation group were significantly higher than those in the control group (P<0.05);PaO2,PaCO2,respiratory rate,and heart rate were significantly lower in the observation group than in the control group (P<0.05). There was no statistically significant difference in the total incidence of adverse reactions between the observation group and the control group (P=0.002). Conclusion Early nasal continuous positive airway pressure ventilation in children with severe pneumonia can effectively shorten the time required for clinical symptom relief,correct hypoxia,improve clinical efficacy,and have high safety.