Expression Levels of NLR,PCT and D-D in Children with Mycoplasma Pneumonia and their Prognostic Value

YANG Guoliang

doi:10.13919/j.issn.2095-6274.J202404019

Abstract：Objective To investigate the expression levels of neutrophil to lymphocyte ratio(NLR),pro-calcitonin(PCT),and D-dimer(D-D)in children with Mycoplasma pneumonia,as well as their role in evaluating disease prognosis.Methods Data analysis was conducted on 81 confirmed cases of Mycoplasma pneumonia in Shaowu Municipal Hospitalfrom September 2021 to September 2023.Referring to the prognosis,66 cases with good prognosis and 15 cases with poor prognosis were divided into two groups.Clinical data of the patients were collected,and the NLR,PCT,and D-D levels of the two groups of patients were tested.We analyzed the predictive value of NLR,PCT,and D-D on the prognosis of children with Mycoplasma pneumonia.Results According to the results of single factor analysis,the difference of WBC,PLT,IL-6,TNF-α,CRP,NLR,PCT,and D-D index val-ues of the two groups were statistically significant(P＜0.05).According to the results of logistic multiple factor re-gression analysis,TNF-α,NLR,PCT,and D-D are risk factors affecting the prognosis of children with Mycoplasma pneumonia(P＜0.05).ROC curve analysis shows that the combination of NLR,PCT,and D-D has a certain predic-tive effect on the prognosis of children with Mycoplasma pneumonia,and the combined prediction AUC(0.974)is higher than the AUC of all single predictions,indicating that the combined prediction has higher value and accuracy in predicting the prognosis of children with Mycoplasma pneumonia.Conclusion NLR,PCT,and D-D are risk factors for the prognosis of children with Mycoplasma pneumonia,and the combined prediction of NLR,PCT,and D-D has higher accuracy in predicting the prognosis of children with Mycoplasma pneumonia than that of all single predictions,indicating higher diagnostic value.