Application Value of Red Blood Cell Irregular Antibody Screening In Emergency Transfusion

CHEN Chunhui; LI Zhimeng

doi:10.13919/j.issn.2095-6274.J202403107

Abstract：Objective To analyze the application value of screening for irregular red blood cell antibodies in emergency blood transfusion.Methods A retrospective analysis was conducted on the data of 4898 prospective blood transfusion patients admitted to Huli District Maternal and Child Health Hospital in Xiamen from January 2019 to December 2023.The results of red blood cell irregular antibody screening and the information of clinical blood transfusion treatment were collected.Results According to the statistics of irregular antibody screening results,out of 1125 patients who planned to undergo blood transfusion,72 patients tested positive for irregular antibody screening,accounting for 1.47％(72/4898).Among the 72 patients with positive irregular antibody screening results,65 patients(90.28％)had a history of pregnancy,6 patients(8.33％)had a history of blood transfusion,28 patients(38.89％)had tumor diseases,26 patients(36.11％)had blood diseases,and 11 patients(15.28％)had other diseases.Among 72 patients with positive irregular antibody screening results,40 received matching blood products and successfully completed emergency blood transfusion treatment without any adverse reactions;20 cases showed false positive screening results due to cross reactivity;12 cases did not find suitable blood donors and did not receive blood transfusion treatment.Conclusion In emergency blood transfusion treatment,screening for irregular red blood cell antibodies in patients who plan to receive blood transfusion can timely grasp the patient's condition,provide reference for clinical blood selection,reduce the occurrence of adverse reactions after transfusion,and ensure blood transfusion safety.