Variation of serum thyroid hormone levels in ifre ifghters injured in the 8?12 Tianjin explosion
WANGXiumei
ZHANGJinhong
DINGQi
YANGXiaoli
HAOQinfang
WANGZhenghui
XIAOXiaojun
andSONGLijie
Abstract：Objective The aim of this study was to investigate the variation of serum thyroid hormone levels in fire fighters injured in the explosion on 8·12 in Tianjin, and to explore the relationship between the thyroid hormone and stress. Methods Total-triiodothyronine (TT3), total thyroxine (TT4), free triiodothyronine (FT3), free thyroxine (FT4) and thyroid-stimulating hormone (TSH) levels of fire fighters before and after injury were analyzed with an immunology analyzer, Johnson Vitros 3600 from America. Results Serum thyroid hormone levels of fire fighters before and after injury as well as at different time points were compared. The results showed statistically significant differences across all time points in TT3 (F=85.95, P<0.05), TT4 (F=27.98, P<0.05), FT3 (F=14.89, P=0.001), FT4 (F=11.96, P<0.05);but the difference in TSH was not significant (F=1.99, P=0.164). The order of degree of variation of the fire fighters' thyroid hormone levels soon after injury was sorted as TSH>T3>FT4>T4>FT3, 24 h after injury it was TSH>FT4>FT3>T3>T4, and TSH>T4>FT3>FT4>T3 48 h after injury. Conclusions Thyroid hormones are involved in the stress response of injured fire fighters, and TT3, TT4, FT3, FT4 can be used as indicators of trauma stress response.
Keywords：stressthyroidhormones
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 65-67 )