Comparison of clinical effect between amiodarone and propafenone in prehospital treatment of paroxysmal supraventricular tachycardia
HU Yuanyang
HONG Jianfang
HE Yingchun
LIN Zhihua
Abstract：Objective To compare clinical efficacy between amiodarone and propafenone in prehospital treatment of paroxysmal supraventricular tachycardia.Methods 78 cases of an emergency command center in PSVT prehospital emergency patients from 2008, January to 2016, February in Fujian province were selected and randomly divided into amiodarone group (n=39) and propafenone group (n=39) treated by corresponding methods, PSVT cardioversion rate, cardioversion time and adverse drug reaction after treatment ,of the two groups were observed.Results The effective cardioversion rate of amiodarone group is slightly higher than that of propafenone hydrochloride group, but there was no significant difference; cardioversion time of the patients in the hydrochloride group was significantly shorter than that in the amiodarone group [(13.1±3.2)vs(24.8±5.3)h ], and the difference was statistically significant (t=2.07,P=0.003); the incidence of adverse reaction in the amiodarone group (5.13%) was less than that of propafenone group (20.51%), and the difference was statistically significant (P<0.05).Conclusions Amiodarone and propafenone both have good effects on the cardioversion of PSVT during prehospital first aid, the therapeutic effect of amiodarone was slightly higher than that of propafenone, and it has less adverse reactions, but its cardioversion time was slower.
Keywords：amiodaronepropafenoneparoxysmal supraventricular tachycardiaprehospital first aid
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 498-500 )