Comparative study on different prognostic scoring system in prognosis evaluation of myelodysplastic syndrome
WANG Wei
WU Guangsheng
Abstract：Objective To explore the significance among different scoring systems in predicting the prognosis of myelodysplastic syndrome (MDS), to guide the clinical accurate prognosis stratification and personal treatment.Methods The clinical data of 72 patients with newly diagnosed MDS were retrospectively reviewed, the prognosis was evaluated according to international prostate symptom score (IPSS), World Health Organization classification-based prognostic scoring system (WPSS) and revised international prognostic scoring system (IPSS-R). Results The difference of median survival time between different groups of prognostic scoring system was statistically significant (Tarone-Ware=9.572-19.834,P<0.05). The survival curve of WPSS had more intersections between each group, IPSS-R prognosis had less intersections. For low risk group, prognostic evaluation of IPSS and WPSS were poor, IPSS-R was the best way to predict the prognosis. Correlation between IPSS and IPSS-R was the strongest (rs=0.765,P<0.05).Conclusions All the three scoring systems can better predict the prognosis of patients with newly diagnosed MDS, and IPSS-R has more advantages. Integrated using 3 scoring system in clinical work is more favorable for clinical prognosis evaluation of MDS.
Keywords：myelodysplastic syndromeprognostic scoring systemsurvival analysis
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 199-202 )