Research progress on pulmonary endothelial gycocalyx and acute lung injury
FANG Chen
ZHANG Jianfeng
Abstract：Located on the luminal surface of vascular endothelial cells,the endothelial glycocalyx is composed of proteoglycan, glycosaminoglycan, glycoproteins and a wide array of molecules from plasma. Pulmonary endothelial glycocalyx serves as a barrier to neutrophil adhersion and extravasation. And it also has an impact on the active regulation of endothelial permeability. Endothelial glycocalyx plays a pivotal role in acute lung injury. Protection or reconstruction of glycocalyx may prove to be a new therapeutic approach for acute lung injury.
Keywords：glycocalyxendothelial cellacute lung injury
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 42-45 )