The guiding function of procalcitonin for the diagnosis and antibiotic therapy of early-onset stroke-associated pneumonia
SHEN Lei
FAN Xizhen
HAN Yongsheng
Abstract：Objective To observe the value of monitoring procalcitonin(PCT) in the diagnosis and guidance of antibiotic therapy for stroke patients with early-onset stroke-associated pneumonia (EOP).Methods 220 cases of acute stroke patients that admitted in the department of emergency internal medicine in Anhui provincial hospital were recruited.The serum level of PCT of two groups were detected:EOP group (n=52) and non-EOP group (n=168) ; patients of EOP group were divided into 2 groups: PCT-guided group (n=27) and non-PCT-guided group (n=25).Length of hospitalization,duration of antibiotics and clinical efficacy were observed.Results When patients were hospitalized,the serum level of PCT in EOP group [(0.83±0.42) ng/ml] was significantly higher than that of non-EOP group [(0.18±0.06) ng/ml] (P<0.01); At the time of diagnosis,the serum level of PCT [(1.83±0.71) ng/ml] of EOP group was significantly increased (P<0.01);the length of hospital stay and antibiotic duration in the PCT-guided group were lower than those in the non-PCT-guided group (P<0.05).Conclusions PCT monitoring not may play a role in the diagnosis of EOP patients,and also can guide the rational use of antibiotics.
Keywords：procalcitoninstrokepneumonia
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 679-682 )