Analysis on nosocomial infection and antimicrobial susceptibility in EICU

ZANG Xiuxian; XU Dahai; ZHANG Nan; PANG Li

doi:10.13919/j.issn.2095-6274.2015.10.008

Abstract：Objective To investigate the etiology distribution, antimicrobial susceptibility and drug resistance in EICU,in order to provide reference for antibiotics use.Methods Clinical cases with nosocomial bacterial infections in EICU of our hospital were analyzed, and then identification and susceptibility of bacteria were detected.Results Bacterial strains were found in 85 cases from 810 patients (10.5%). Sputum culture positive rate is 85.9%, blood culture positive rate is 14.1%, and midstream urine culture and central venous tip segment culture have not bacterial growth in samples of the 85 patients. Gram-negative bacilli are the primary pathogens among all bacteria detected, and the ratio of E.coli, acinetobacter baumannii and klebsiella pneumoniae were 22.4%, 21.2% and 5.9% respectively. Drug susceptibility test results showed that bacterial resistance significantly increased. Most of gram-negative bacteria had high sensitivity to meropenem, cefoperazone/sulbactam, piperacillin/tazobactam and amikacin; and gram-positive bacteria were highly sensitive to vancomycin and linezolid..Conclusions Nosocomial infections in EICU are mostly resistant strains. It is important to strengthen monitoring of bacterial infection and antibiotic resistance to reduce incidence of nosocomial infections.