The Evaluation Value of Residual Cholesterol Inflammatory Index in Assessing the Degree of Coronary Artery Lesions in Cases with Coronary Heart Disease
TONG Xiaoyue
WANG Hongxia
WANG Jing
CHEN Qianru
XU Yanjuan
Abstract：Objective To analyze the value of residual cholesterol inflammatory index(RCII)in assessing the degree of coronary artery lesions in patients with coronary heart disease.Methods A total of 206 patients with coronary heart disease admitted to Nanjing Central Hospital from March 2022 to March 2025 were enrolled.According to the Gensini score,patients were divided into a mild group(n=109)and a severe group(n=97).Differences in total cholesterol,triglycerides,high-den-sity lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),high-sensitivity C-reactive protein(hs-CRP),RC and RCII were compared between groups.Receiver operating characteristic(ROC)curve analysis was used to eval-uate RCII's value in assessing coronary lesion severity.Multivariate logistic stepwise regression analyzed influencing factors.Results Triglycerides,RC,hs-CRP and RCII were significantly higher in the severe group than in the mild group(P<0.05),while HDL-C was lower(P<0.05).The AUC(95%CI)of RCII for assessing coronary lesion severity was 0.901(0.850-0.953),significantly higher than that of triglycerides[0.632(0.582-0.683)],HDL-C[0.740(0.691-0.792)],RC[0.847(0.795-0.893)]and hs-CRP[0.768(0.717-0.819)]alone(Z=11.021,10.654,8.184,9.461;all P<0.05).Fasting blood glucose,white blood cell count,and serum creatinine were higher in the severe group,with higher proportions of hypertension and diabetes history,while left ventricular ejection fraction was lower(all P<0.05).Multivariate analysis identified hypertension(OR=2.804,95%CI:1.418-5.546),elevated fasting blood glucose(OR=1.982,95%CI:1.326-2.962),elevated RC(OR=2.130,95%CI:1.365-3.323),and elevated RCII(OR=2.323,95%CI:1.469-3.675)as independent risk factors(all P<0.05).Conclusion RCII is signifi-cantly correlated with the degree of coronary artery lesions in cases with coronary heart disease and can predict the degree of coronary artery lesions more accurately than a single indicator.
Keywords：Coronary heart diseaseCoronary artery lesionsResidual cholesterol inflammatory indexAssessing value
Publication Date：2025-07-20
Online Publishing Date：2025-08-27(First online date of this platform, not the publication date of the document)
Pages：5( 30-34 )