The Relationship between Paravertebral Muscle CT Values and Refractures after Percutaneous Vertebroplasty in Patients with Osteoporotic Lumbar Fractures
LIU Zuyao
LI Qiang
LI Fu
ZHANG Hongjian
YANG Deng
LǓ Zhaohui
Abstract：Objective To investigate the relationship between paravertebral muscle CT values and re-fracture after percutaneous vertebroplasty(PVP)in patients with osteoporotic lumbar fracture.Methods A total of 120 cases with osteo-porotic lumbar fracture who underwent PVP from April 2022 to April 2023 were selected.All patients received 1-year radio-graphic follow-up.According to the occurrence of osteoporotic vertebral refracture,120 patients were divided into refracture group(n=26)and non-refracture group(n=94).The CT values of paravertebral muscles(mean CT values of posterior vertebral muscles and mean CT values of psoas major muscles)were measured in all subjects.Spearman correlation analysis was used to investigate the relationship between paravertebral muscle CT value and re-fracture after PVP.Receiver operating character-istic(ROC)curve analysis was used to analyze the predictive value of paravertebral muscle CT value on re-fracture after PVP,and multi-factor logistic regression was used to analyze the influencing factors of re-fracture after PVP.Results The average CT values of posterior vertebral muscle group and psoas major muscle in refracture group were lower than those in non-refrac-ture group(P<0.05).The mean CT values of posterior vertebral muscle group and psoas major muscle in patients with osteopo-rotic lumbar fracture were negatively correlated with refractures after PVP(P<0.05).The AUC of posterior vertebral muscle and psoas major muscle were 0.731(95%CI:0.681-0.776)and 0.849(95%CI:0.799-0.894),respectively,and the AUC of com-bined prediction was 0.907(95%CI:0.857-0.952).The age,body mass index,bone cement injection amount and the proportion of bone cement leakage in the re-fracture group were higher than those in the non-re-fracture group,and the bone mineral density T value was lower than that in the non-re-fracture group(P<0.05).Age(OR=1.893,95%CI:1.150-3.114),bone cement leakage(OR=2.067,95%CI:1.249-3.420),bone mineral density(OR=2.649,95%CI:1.626-4.315),bone cement injection volume(OR=2.368,95%CI:1.491-3.761),average CT value of posterior vertebral muscle group(OR=2.821,95%CI:1.658-4.798),average CT value of psoas major muscle(OR=3.267,95%CI:1.944-5.493)were the influencing factors of re-fracture after PVP(P<0.05).Conclusion Paravertebral muscle CT is negatively correlated with refracture after PVP.Lower average CT values of posterior vertebral muscle group and psoas major muscle are important influencing factors for refracture after PVP.
Keywords：Osteoporotic lumbar fracturePercutaneous vertebroplastyRefracturecorrelation
Publication Date：2025-03-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 50-55 )