Ultrasound BI-RADS Quantitative Ultrasound Score Combined with Elastic Strain Rate Ratio Diagnostic Value for Benign and Malignant Breast Nodules
ZHANG Xiuling
FU Liyu
ZHANG Weijiao
WANG Xiaohui
Abstract：Objective To investigate the value of ultrasonic quantization score and elastic strain rate ratio(SR)com-bined with serum anticancer Pro153(CA153)in benign and malignant breast nodules by Ultrasonic Breast Imaging Report and Data System(BI-RADS).Methods A total of 83 patients with breast nodules(52 malignant and 31 benign),selected based on pathological tissue examination results as the"gold standard,"were included in this retrospective analysis.These patients were treated at the Physical Diagnosis Department of East Hospital of Jiamusi Central Hospital,from January 2022 to January 2024.The BI-RADS quantitative score,SR,and serum CA153 of all subjects were collected.The diagnostic prediction model was constructed by drawing a nomogram,and the predictive ability of the nomogram model was evaluated by drawing receiver characteristic curve(ROC curve)for internal verification.Results The accuracy of BI-RADS quantitative score and SR di-agnosis of breast nodules,evaluated based on pathological examination results as the"gold standard,were 84.34%and 86.75%,the sensitivity was 91.49%and 91.84%,and the specificity was 75.00%and 79.41%.The serum CA153 index of malignant breast nodules was higher than that of benign breast nodules(t=17.651,P<0.05).A nomogram prediction model was established,and the AUC value in the ROC curve was 0.999(95%CI:0.998-1),indicating that the clinical prediction model had a good risk prediction degree.Conclusion BI-RADS quantitative score,SR,and serum CA153 have high clinical value in the identifi-cation of benign and malignant breast nodules.The prediction model based on the above indicators can screen high-risk groups and provide theoretical guidance for clinical practice.
Keywords：Breast nodulesUltrasound breast imaging reporting and data systemElastic strain rate ratioCombined diagnosis
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1830-1833 )