Establishment and Research of an Early Precise Assessment and Early Warning Model for Mortality Risk in Septic Shock Patients
LUO Xiaobo
CAI Kun
CHEN Xuehua
Yu Tianbo
Abstract：Objective To establish a model for predicting the death of septic shock patients through data analysis by combining the vasoactive inotropic score(VIS),the Modified Critical Care Ultrasound Examination Score(MCS),and procalcitonin(PCT),evaluate and apply the model to guide the early treatment of septic shock patients.Methods A retrospective analysis of clinical data from 320 inpatients in the intensive care unit of Zigong Fourth People's Hospital from August 2022 to March 2024 was used as the data source.Based on the patients'prognosis,those who died within 28 days were included in the Death Group(n=48),and those who survived were included in the Survival Group(n=272).Multivariate binary logistic regression analysis was used,and ROC curve analysis was performed on the significant influencing factor indicators for death.Results The VIS score,MCS score,and PCT level are risk factors for mortality in patients with septic shock.The predictive model for death in septic shock patients was established as follows:L=VIS+2.131 × MCS+1.017 × PCT.The combined predictive factor L had significant predictive value for death,with an AUC of 99.1％,P＜0.05,a cutoff value of 131.15,a sensitivity of 97.92％,and a specificity of 94.49％.Based on the AUC,the order of predictive value was L＞VIS＞MCS＞PCT.Conclusion The prediction model of Vaso-active Inotropic Score combined with Modified Critical Care Ultrasound Examination Score and procalcitonin for predicting death in septic shock patients can be applied in clinical practice and has important guiding significance for the early and precise treat-ment of septic shock.
Keywords：Septic ShockVasoactive Inotropic ScoreModified Rapid Management Protocol Score for Critical Care Ul-trasoundMortality RateROC curve
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1408-1413 )