Effect of Different Positioning Methods on Fixation Accuracy of Positioning in Intensity-Modulated Conformal Radiation of Cervical Cancer
HU Shengrong
MIAO Jidong
ZHOU Jixiang
GUAN Wenqiang
Abstract：Objective To analyze the influence of different positioning methods on the fixation accuracy of position-ing during intensity-modulated conformal radiation therapy of cervical cancer.Methods A total of 98 patients with cervical cancer treated from June 2022 to April 2024 were selected,all of whom were treated with intensity-modulated radiotherapy.The patients underwent cone beam computed tomography(CBCT)under the treatment machine during therapy.Forty-eight patients were grouped according to different positioning methods.Fifty cases fixed by integrated frame and thermoplastic film with vacuum pad were included in group B.The qualified rate and error of positioning,dose distribution in the planned target area,radiation dose to small intestine,rectum,and bladder,incidence of radiation-related toxicity,and subjective comfort satisfaction of patients were compared between the two groups.Results The qualified rate of group A was 67.92％(163/240),lower than that of group B,89.20％(223/250)(P＜0.05).The error on the X-axis and Y-axis in group A was higher than that in group B(P＜0.05).The percentage of 95％planned dose in the planned target area(V95％),the dose of V100％,and V105％in group A were lower than those in group B(P＜0.05).The maximum radiation dose(Dmax),minimum radiation dose(Dmin),percentage of the total volume of the organ receiving 10 Gy or above dose(V10),V20,and V50 to small intestine,rectum,and bladder in group A were higher than those in group B(P＜0.05).The incidence of radiotherapy-related toxicity in group A was 58.33％(28/48),higher than that in group B,38.00％(19/50)(P＜0.05).The subjective comfort satisfaction of group A was 56.25％(27/48),lower than that of group B,84.00％(42/50)(P＜0.05).Conclusion The application of an integrated frame,vacuum pad,and thermoplastic film in intensity-modulated conformal radiotherapy for cervical cancer can effectively reduce the positioning error,more accurately control the planned target area and the radia-tion dose to endangered organs,reduce the occurrence of toxic effects,and improve the comfort of patients.
Keywords：Cervical cancerIntensity-modulat-ed conformal radiationThermoplastic filmPositioning and FixationVacuum pad
Publication Date：2024-10-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1315-1320 )