Effect of Microsurgical Treatment of Parasagittal and Parafalcine Meningi-omas and Analysis of Prognostic Factors
ZHANG Jian
ZHANG Yonghui
QU Chengbin
YANG Aoran
HU Yaofeng
HONG Yang
Abstract:Objective To investigate the effect of microsurgery in the treatment of parasagittal and parafalcine menin-giomas and to analyze the relevant prognostic factors.Methods We retrospectively analyzed the clinical data of 52 patients with parasagittal and parafalcine meningiomas treated by microsurgery from April 2013 to January 2021,and followed them up for 3 to 12 months after surgery.The patients were scored and grouped by Karnofsky Performance Status Score Scale(KPS),and the patients with KPS score≥90 were classified as good prognosis group,while those with KPS score<90 were classified as poor prognosis group.The preoperative symptoms,tumor characteristics,Simpson grading,postoperative complications and recurrence were compared between the two groups,and the influencing factors of the prognosis were analyzed.Results Among 52 cases,35 cases had good prognosis and 17 cases had poor prognosis.There was one case of intracranial hemor-rhage,one case of intracranial infection and one case of tumor recurrence after surgery.Multivariate logistic regression analysis showed that tumor diameter,Simpson grading and preoperative motor disorder were independent risk factors for poor postopera-tive prognosis in patients with parasagittal and parafalcine meningiomas(P<0.05).Conclusion Microsurgery can effective-ly improve the prognosis of patients with parasagittal and parafalcine meningiomas with a high rate of total resection,but tumor diameter,Simpson grading and preoperative motor disorders can affect the prognosis of patients.
Keywords:MeningiomaSagittal sinusFalx cerebriMicrosurgerySimpson gradingPreoperative motor disor-dersRisk factorsPrognosis
Publication Date:2023-10-20
Online Publishing Date:2025-08-15(First online date of this platform, not the publication date of the document)
Pages:5( 250-254 )
Translational Medicine Journal

Translational Medicine Journal

ISTIC
ISSN:2095-3097
Year, Vol.(Issue):2023,12(5)