Research progress of signal transducers and activators of transcription signal pathway in natural killer cell
YU Huaihai
SUN Yufei
JIN Changzhu
FU Qiang
Abstract：Natural killer ( NK) cells play a critical role in anti-tumor immunity, anti-infec-tion immunity and reproductive immunity. The study of its signaling pathway is helpful for us to bet-ter understand the biological behavior of NK cells. Signal transducers and activators of transcription ( STAT) signaling pathway is one of the most studied pathways in recent years which plays an impor-tant role in the growth, development and functional regulation of NK cells. In this paper, we re-viewed the recent progress of STAT signaling pathway in NK cells to promote the application of NK cell in translational medicine.
Keywords：Natural killer ( NK ) cellSignal transducers and activators of transcription ( STAT) signal pathwayTumor immunologyInfection immunologyReproductive immunology
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 188-193 )