Research progress in surface markers of liver cancer stem cells and their applications in clinical diagnosis and treatment
CHAO Xu
ZHAO Jiarong
ZHANG Yanfang
Abstract：Liver cancer is one of the most common malignant tumors in our country, it has the characteristics of high incidence and postoperative metastasis,which has been a hot topic in clin-ical research. Liver cancer may be caused by liver cancer stem cells (LCSC) differentiation, this provides new ideas for liver cancer treatment. In recent years, from liver cancer tissue and cells a variety of surface markers have found. Normal cells have no expression or low expression, while on the surface of LCSC specifically with high expression. These markers have become the target and ba-sis for early diagnosis and treatment of hepatocellular carcinoma. In this review,the surface markers of LCSC related to liver metastasis,recurrence and their applications in clinical diagnosis and treat-ment are reviewed.
Keywords：Liver cancerStem cellsBiomarkers
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 125-128 )