The basic and clinical research progress of myocardial ischemic conditioning
ZHAO Li
LI Yajun
ZHANG Boyang
WANG Dongjuan
LI Dongtao
LI Xianfeng
CHEN Yu
LI Tianchang
Abstract：Conditioning is the intrinsic mechanism that an organ protects itself from fetal inju-ries. Myocardial ischemic preconditioning means repeated short-term ischemia-reperfusion could pro-tect the myocardium from fetal injuries. Further research revealed other phenomena including post-conditioning, remote conditioning and drug simulated conditioning which could all protect the myo-cardium. Although there is immense interest in the conditioning phenomenon, its clinical application was limited, largely as result of unstandardized procedure, and various influencing factors. With re-mote ischemic conditioning regarded as one of the most promising non-invasive myocardial protecting measures, the success of its clinical translation may need further well designed, large size and pro-perly conducted clinical trials.
Keywords：Myocardial infarctionIschemia-reperfusion injuryIschemia conditioningTranslational medicine
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 317-320 )