Efficacy of dexamethasone in combination with thrombopoietin and ciclosporin in the treatment of immune thrombocytopenia
GUO Honggang
WANG Jiajia
CEN Jian
LIU Yi
SHEN Jianlian
Abstract：Objective To investigate the treatment efficacy of immune thrombocytopenia (ITP) by high-dose dexamethasone combined with thrombopoietin and ciclosporin (Cs). Methods Fifty-five cases of immune thrombocytopenia patients were randomly divided into two groups, the ob-servation group with dexamethasone, recombinant human thrombopoietin ( rhTPO) and Cs, and the control group with dexamethasone and rhTPO. The short-term effect, long-term efficacy and side effects between the two groups were compared. Results There were no significant differences in short-term effect, long-term efficacy in observation group was significantly better than that in the control group. One case in each group reduce the dosage of dexamethasone for side effects. Conclu-sion Addition of Cs in patients with ITP who have recent good effects after the use dexamethasone and rhTPO can improve the long-term effectiveness.
Keywords：Immune thrombocytopenia ( ITP )ThrombopoietinCiclosporin ( Cs)Combi-nation therapy
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 279-282,297 )