The effect of ator vastatin calcium tablets on C-reactive protein, interleukin-6 and pulmonary function in chronic obstructive pulm onary disease patients of stationary phase
ZHANG Rongchang
ZHANG Shuai
LUO Yuxiong
Abstract：Objective To observe the effect of atorvastatin calcium tablets on C-reactive pro-tein( CRP ) , IL-6 and pulmonary function in chronic obstructive pulmonary disease patients of sta-tionary phase.Methods Sixty patients in stationary phase of chronic obstructive pulmonary disease ( COPD) were randomly divided into treatment group and control group.Patients in the control group ( n=30) were treated with conventional therapy, and those in the treatment group were given oral atorvastatin calcium tablets 20 mg on the basis of routine treatment, once per night.The course of treatment was 1 year.The levels of CRP, interleukin ( IL)-6 and the CAT scores and pulmonary function were measured before and after treatment, continuously followed for 2 years.Results The difference in the levels of of CRP , IL-6 and the CAT scores between the two group before treatment were not statistically significant (P>0.05).After 1 year of treatment, levels of CRP, IL-6 in the treatment group were significantly lower than those in the control group ( P<0.05) .CAT scores of the treatment group was significantly better than the control group ( P<0.05 ) .Conclusion Ator-vastatin calcium tablets can reduce levels of CRP, IL-6 in COPD patients of stationary phase and improve the quality of life.
Keywords：Atorvastatin calcium tabletsChronic obstructive pulmonary disease (COPD)Quality of life
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 282-284 )