Significance of calcification in the differential diagnosis of thyroid nodules
GUAN Jin
LI Jinrang
ZHANG Yunshan
Abstract：Objective To assess the significance of thyroid microcalcification and macrocal-cification of ultrasonography (US) in the differential diagnosis of thyroid nodules.Methods A total of 142 patients with thyroid nodules included in this study.The calcification of the thyroid nodules observed by US were recorded and compared with the data of postoperative pathological results.Re-sults A total of 152 thyroid nodules were found in 142 patients.Postoperative histopathologic re-sults revealed 99 nodules were benign and 53 were malignant.There were 42 (79.25%) nodules with calcification in 53 malignant nodules, including 39 (73.58%) microcalcification nodules and 3 (5.66%) macrocalcification nodules.There were 15 (15.15%) nodules with calcification in 99 be-nign nodules, including 8 (8.08%) microcalcification nodules and 7 (7.07%) macrocalcification nodules.The sensitivity and specificity of microcalcification in diagnosis of thyroid cancer were 73.58% and 91.92% respectiviely.The sensitivity and specificity of macrocalcification in diagnosis of thyroid cancer were 5.66% and 92.93% respectively.Conclusion Microcalcification by US could be used to predict the risk of malignant thyroid nodules, while macrocalcification could not.
Keywords：CalcificationNeoplasmThyroidDifferential diagnosis
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 226-228 )