Analysis of effectiveness and security of etoprolol succinate sustained-release tablets in treating the elder patients of permanent atrial fibrillation with fast ventricular rate
BIAN Ning
TIAN Haitao
Abstract：Objective To analysis of effectiveness and security of metoprolol succinate sus-tained-release tablets in treating the elder patients of permanent atrial fibrillation with fast ventricular rate .Methods Forty elder patients of permanent atrial fibrillation with fast ventricular rate were en-rolled in the trial , they were given small dose metoprolol tartuate tablet orally and gruadually in-creased dosage for 2 weeks.Then replaced by metoprolol succinate sustained-release tablets with ratio of 1∶1 and observed for 2 weeks.The patients symptom, 24 h mean heart rate, morning resting heart rate, mean blood pressure, and brain natriuretic peptide (BNP) individually recorded and analyzed . Results The average of target dose of metoprolol was ( 66.25 ±18.75 ) mg.Metoprolol succinate sustained-release tablets could improve patients symptom , 24 h mean heart rate , morning resting heart rate , mean blood pressure and BNP ( P<0.05 ) .By analysis with the holter , there were not found more longer R-R intervals when rearch the tartuate tablet (P>0.05).Conclusion In treating the elder patients with permanent atrial fibrillation with fast ventricular rate , metoprolol succinate sustained-release tablets are effectiveness and security , and worth to use in clinic .
Keywords：Metoprolol succinate sustained-release tabletsPermanent atrial fibrillation with fast ventricular rateEffectivenessSecurityElder
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 145-147 )