Long non-codi ng RNA, potential biomarkers of the cancer diagnosis
XUF eiyue
CHEN Yangchao
Abstract：[Large numbers of the genomic transcripts do not encode proteins but play critical role in development and progress of cancer.Those non-coding transcripts are called non-coding RNA.Among the non-coding RNA, the long non-coding RNA (lncRNA) are increasingly recog-nized as participators of gene regulation.Parts of the lncRNA are found to be dysregulated in cancer and believed to be potential biomarkers for cancer diagnosis .In this paper, the classification, regu-lation mechanisms and biological functions of the lncRNA are introduced.Besides, some existing and potential biomarker lncRNA are also elaborated here.More lncRNA will be investigated and be-come the significant biomarkers for cancer diagnosis with the advancement of gene sequence and mi-croarray technologies.
Keywords：Long non-coding RNA ( lncRNA)Regulation mechanismsTumorGene diagnosis
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：8( 257-264 )