Study on the mosquito repellent activity of Tripterygium wilfordii extract against Aedes albopictu and Aedes aegypti
WU Kunyang
QIAO Mengling
YUE Na
ZHENG Weiqing
LI Siping
YAN Yinuo
YAN Liu
HU Dan
TAN Weilong
Abstract：Objective To explore the repellent effect of natural active ingredients,and investigate the repellent effect of Tripterygium wilfordii extract against Aedes albopictus and Aedes aegypti.Methods The repellent effect of T.wilfordii extract and its mosquito repellent milk were determined by attack test and repellent test.The content of triptolide in the extract was analyzed by high performance liquid chromatography(HPLC).Results T.wilfordii extract had a good repellent effect on Ae.albopictus,and the concentration was positively correlated with the average effective protection time.At the concentration of 35 g/kg,the average effective protection time reached 5.0 h.Further,the T.wilfordii extract was processed into mosquito repellent milk for repellent activity test,and it was found that the mosquito repellent milk had a good repellent effect on Ae.albopictus and Ae.aegypti,and the average effective protection time reached 5.0 h and 3.7 h at the concentration of 30 g/kg,respectively.The results of HPLC showed that the extract contained 0.007 2％triptolide,the landmark active ingredient.Conclusion T.wilfordii extract has good mosquito repellent activity and possesses the development potential for plant-derived mosquito repellent products.
Keywords：Tripterygium wilfordii extracttriptoliderepellentAedes albopictusAedes aegypti
Publication Date：2026-02-20
Online Publishing Date：2026-04-02(First online date of this platform, not the publication date of the document)
Pages：5( 56-60 )