Guidelines for diagnosis and treatment of central nervous system germinoma in Chinese children and adolescents(Version 2026)
PEDIATRIC NEUROSURGERY GROUP OF THE CHINESE SOCIETY OF NEUROSURGERY,CHINESE MEDICAL ASSOCIATION
MA Jie
CHEN Zhongping
ZHANG Rong
Abstract：Central nervous system germ cell tumors are common malignant tumors in children and adolescents,often occurring in the pineal region,sellar region or basal ganglia-thalamus region,and in a few cases,multiple intracranial lesions may exist.Due to the differences in tumor location,clinical manifestations,and pathological types,treatment methods and prognosis vary.The treatment of central nervous system germ cell tumors is rather complex.The common treatment for pure central nervous system germ cell tumors is surgical biopsy to confirm the pathology,followed by chemotherapy combined with radiotherapy or radiotherapy alone,which can achieve good clinical outcomes.The Pediatric Neurosurgery Group of the Chinese Medical Association's Neurosurgery Branch has formulated the diagnosis and treatment guidelines for pure central nervous system germ cell tumors in Chinese children and adolescents based on domestic and international clinical research and experience.This guideline covers the integrated diagnosis and treatment plans for primary and recurrent central nervous system pure germinoma in patients over 3 years old,aiming to standardize the diagnosis and treatment of such patients in China and further improve their therapeutic efficacy.
Keywords：GuidelineGerm cell tumorCentral nervous systemChildrenGerminomaChemotherapyRadiotherapy
Publication Date：2026-02-28
Online Publishing Date：2026-03-13(First online date of this platform, not the publication date of the document)
Pages：7( 1-7 )