Research progress of isoliquiritigenin in neurorepair
JIANG Yipeng
ZHANG Jianan
HAN Yongming
ZHOU Jie
LI Changdong
CAO Li
Abstract：Neurological disorders have become a serious public health challenge in today's society,and isoliquiritigenin(ISL),as a natural compound,has shown potential roles in neurorepair and combating neurological diseases.This compound demonstrates broad therapeutic prospects for various neurological disorders through multiple pharmacological mechanisms,including anti-inflammatory,antioxidant,immune-regulating effects,promoting neuronal growth,and reducing neuronal apoptosis.Studies in animal models have shown that isoliquiritigenin can improve the pathophysiological processes in models of Alzheimer's disease,traumatic brain injury,and subarachnoid hemorrhage,providing a foundation for its application in the treatment of human neurological diseases.This article mainly summarizes the current domestic and international research on ISL in the field of neural injury,offering new insights and potential strategies for the treatment of neurological disorders.
Keywords：isoliquiritigeninneurorepairalzheimer's diseasetraumatic brain injurysubarachnoid hemorrhage
Publication Date：2026-01-28
Online Publishing Date：2026-01-17(First online date of this platform, not the publication date of the document)
Pages：6( 114-119 )