Prognosis of endovascular treatment for unruptured intracranial aneurysms in elderly patients

ZHAO Yulong; BAI Yang; CHEN Ligang; XIONG Jian; LIANG Guobiao; GAO Xu

Abstract：Objective To explore the prognosis and related risk factors of endovascular treatment for unruptured aneurysms in elderly patients.Methods The clinical data of 623 elderly patients with unruptured intracranial aneurysms(UIAs)who underwent embolization of intracranial aneurysms in the Department of Neurosurgery of the General Hospital of the Northern Theater Command of the Chinese People's Liberation Army from January 2013 to December 2020 were retrospectively analyzed,with a focus on the risk factors.Results Out of the 623 patients,57(9.15%)experienced perioperative complications.Results of univariate analysis showed that gender(P=0.006),hypertension(P<0.001),coronary heart disease(P<0.001),severe stenosis of other intracranial vessels(P<0.001),previous TIA attacks(P=0.007),history of old cerebral infarction(P=0.004),renal dysfunction(P=0.021),multiple aneurysms(P<0.001),irregular aneurysm morphology or sub aneurysms(P<0.001)were associated with the occurrence of perioperative complications.Results of multivariate analysis showed that previous TIA attacks,coronary heart disease,and irregular or sub tumor morphology of aneurysms were independent risk factors for perioperative complications.Conclusions Previous TIA attacks,coronary heart disease,and irregular or sub aneurysm morphology are independent risk factors for poor prognosis after endovascular treatment for unruptured intracranial aneurysms in elderly patients.