The related factors of cerebrospinal fluid leakage in acoustic neuroma surgery

BILALI·Balajiang; ZHU Guohua; MAIMAITILI · Mijiti; PEI Yinan; LIU Chen; GENG· DANGMUREN ·Jiafu

Abstract：Objective The related factors of cerebrospinal fluid leakage in acoustic neuroma (vestibular schwannoma) surgery were investigated.Methods From June 2014 to December 2016,90 patients with acoustic neuroma were treated with surgical approach from sub-occipital sigmoid sinus.Microscopic resection of the tumor was performed under facial nerve monitoring.The data of patients with and without cerebrospinal fluid leakage after auditory neuropathy surgery were compared including age,sex,tumor size,location of the tumor,with/without recurrence of the tumor,with/without the internal auditory canal (IAC) expansion,the degree of gasification of the rock,intra-operative removal of the internal auditory canal wall,operative time,combined with diabetes and body mass index (BMI) and other factors,retrospectively.The related factors of cerebrospinal fluid leakage after acoustic neuroma surgery were analyzed.Results In these factors considered,only the intra-operative removing of the posterior wall of the auditory canal (OR:3.58,95％ CI:1.022 ～ 12.536;P =0.046),the operative time (OR:1.008,95％CI:1.001 ～1.016;P =0.029) and the course of the disease (OR:1.011,95％ CI:1.001 ～1.023;P =0.040) were significantly different between the two groups.Conclusion The related factors of auditory cerebrospinal fluid leakage in acoustic neuroma include drilling of the posterior wall of the internal auditory canal,the operative time and the course of the disease.