Curative efficacy of anterior temporal lobe and hippocampus resection for intractable temporal lobe epilepsy
WANG Jianbing
LIU Yongjian
WANG Yangang
Abstract：Objective The curative efficacy of anterior temporal lobe and hippocampus resection for intractable temporal lobe epilepsy was discussed.Methods The data of 46 patients with intractable temporal lobe epilepsy was analyzed,and all these patients were conducted video electroencephalogram (V-EEG),magnetic resonance imaging (MRI),positron emission tomography (PET) and single photon emission computed tomography (SPECT) for preoperative comprehensive evaluation.Extensive pterional approach was applied in the surgery,and anterior temporal lobe and hippocampus resection was implemented by the monitoring of electrocorticogram (ECoG) during operation.After operation,all the patients were followed up for 6 months to 24 months.Results Out of 46 patients,no patients died during operation and no obvious complications occurred.According to Engel classification,there were 37 cases (80.43％) of Class Ⅰ,5 cases (10.87％) of Class Ⅱ,2 cases (4.35％) of Class Ⅲ,and 2 cases (4.35％) of Class Ⅳ.Conclusion Anterior temporal lobe and hippocampus resection is effective in the treatment of patients with intractable temporal lobe epilepsy.Comprehensive pre-operative assessment for the accurate location of epileptogenic foci is the key to improve the curative efficacy,and the profound understanding for anatomical structure of temporal lobe and refined surgical skills can reduce the incidence of post-operative complications.
Keywords：Intractable temporal lobe epilepsyAnterior temporal lobe and hippocampus resectionSurgeryCurative efficacy
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 542-546 )