Evaluation on clinical effect of microsurgical treatment of the fourth ventricular tumors: report of 52 cases

PEI Yinan; ZHU Guohua; MAIMAITILI· Mijiti; LIU Chen; GENG · Dangmurenjiafu

Abstract：Objective The dinical effect of microsurgical treatment of the fourth ventricular tumors was investigated.Methods A total of 52 cases of the fourth ventricle tumors,which were admitted to our hospital from January 2014 to January 2017,were analyzed retrospectively,including 4 cases by cerebellar vermis approach,34 cases by transcerebella medulla oblongata approach and 14 cases by combined approach.According to whether the patients with obstructive hydrocephalus before operation,all the cases were divided into two groups:Group A,with different degrees of obstructive hydrocephalus;Group B,without obstructive hydrocephalus.KPS Scale (Karnofsky) after one week were analyzed and compared between two groups.Results Total resection achieved in 44 cases (84.6％) and subtotal resection in 8 cases (15.4％).The total remission rate of intracranial hypertension was 84.2％.The remission rate of dizziness was 85.3％,the remission rate of vomit was about 94.4％,the remission rate of vision abating was 0,the remission rate of dysphagia was 33.3％,and the remission rate of ataxia was 75％.Postoperative 1 w KPS score showed:the prognosis of patients in Group B was better than those in Group A.The difference was statistically significant (P ＜0.05).Forty cases were followed up,and tumor recurrence occurred in 2 cases and death in 1 case.Conclusion In order to improve the effect of surgical treatment of the fourth ventricle tumor,the choice of appropriate surgical approach,good surgical technique and effective treatment of complications are important.Hydrocephalus before operation has certain effect on the prognosis.