Application of 3D PC and 3D TRICKS on cerebral venous sinus disease:a comparative study

NING Dianxiu; TANG Lemei; DU Minan; ZHANG Jun; MIAO Yanwei; CHEN Guolong

Abstract：Objective The features of 3D Time Resolved Imaging of Contrast Kinetics (3D TRICKS) and 3D Phase contrast (3D PC) in cerebral venous sinus diseases are compared to provide the implication for clinical practices.Methods Fifty patients with cerebral venous sinus thrombosis (CVST) were enrolled into this study (19 males, 31 females;age ranged from 25 to 56 years).The patients all underwent MR scan with GE Signa HDxt 1.5T and Signa HDxt 3.0T MR scanner using 8 Channel head&neck coil.After the head and neck sagittal 3D PC scan, the 3D TRICKS was performed after 0~5 seconds of the administration, and the 25~30 ml contrast agent was bolused with the flow of 3 ml/s, and then acquired 15 phases images.The raw data was processed with functional tool of volume reconstruction and enlarge measurement on the GE ADW 4.4 Workstation.The displaying capabilities on intracranial venous and thrombus were compared between 3D PC and 3D TRICKS sequences.Results In 50 patients with cerebral venous diseases, both two methods revealed 57 lesions in cerebral venous sinuses.The affected sinus lumen exhibited as stenosis, interrupt, filling defect and branches tortuous expansion.In 3D PC images, the main part of cerebral venous sinus was showed clearly, while the vascular continuity was poor, especially in the region of confluens sinuum with lumen interruption.Compared to those in 3D PC images, cerebral veins in 3D TRICKS image were ill-defined border and had better continuities.Statistical data analysis was done with the statistical software SPSS 19.0,andP<0.05wasconsideredasstatisticallysignificant.Conclusion 3DPCand3DTRICKSbothareeffective sequences in diagnosis of CVST.The diagnostic accuracy is basically the same, but the image details are slightly different.