Factors affecting diagnostic yield of stereotactic biopsy in non-enhancement brain lesions
ZHAO Siyuan
ZHANG Jianning
CHANG Hongbo
SUN Yanjie
LIU Juan
YIN Feng
TIAN Zengmin
Abstract：Objective The factors affecting diagnostic yield of stereotactic biopsy in non-enhancement brain lesions are discussed.Methods Ninety-two patients with non-enhancement brain lesions underwent MRI-guided stereotactic biopsy.Clinical features, lesion characteristics, pathological diagnosis and post-operative complications were summarized.The factors affecting diagnostic yield were analyzed.Results Seventy-seven patients had definitive pathological diagnoses.The diagnostic yield in this series was 83.7%. The procedure-related complication morbidity was 2.2%.Multivariate Logistic regression analysis showed that the biopsy diagnostic yield of superficial ( cortical) lesions was significantly decreased compared to that of deep (non-cortical) lesions (odds ratio (OR):3.937;95%confidence interval:1.224~12.662;P<0.05).The other factors did not significantly correlate with the diagnostic yield.Conclusion Stereotactic biopsy is advantageous to obtain accurate pathological diagnosis of non-enhancement brain lesions.The diagnostic yield of cortical lesions is lower than that of non-cortical lesions.
Keywords：Stereotatic techniquesBiopsyBrain diseasesMagnetic resonance imaging
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 242-246 )