Effects of intermittent hypoxic exposure combined with aerobic exercise on physical function in overweight or obese children
Huang Dan
Wang Qing
Zhang Qihan
Li Yu
Ji Xunming
Wang Yuan
Abstract：Objective To explore the effects of intermittent hypoxic exposure combined with aerobic exercise on physical function in overweight or obese children.Methods A total of 38 overweight or obese children(26 boys and 12 girls)were recruited in Beijing Xiaotangshan Hospital from July 2023 to August 2024.A self-controlled before-and-after study design was adopted.All participants received a 3-week intervention of intermittent hypoxic exposure combined with aerobic exercise.Changes in body weight,body mass index,fat mass,body fat percentage,blood lipids,serum uric acid and fatty liver status were compared before and after intervention.Results After intervention,the overall levels of body weight,body mass index,fat mass,body fat percentage,serum total cholesterol,low-density lipoprotein cholesterol,high-density lipoprotein cholesterol and serum uric acid were significantly lower than those before intervention(all P＜0.05).Among the 38 children,16 cases were complicated with fatty liver(6 boys and 10 girls).Before intervention,the severity of fatty liver was mild in 3 cases(18.8％)and moderate in 13 cases(81.2％).After intervention,there were 5 cases without fatty liver(31.3％),10 mild cases(62.5％)and 1 moderate case(6.2％).The severity of fatty liver was significantly improved after intervention(Z=-2.646,P=0.008).Conclusion Intermittent hypoxic exposure combined with aerobic exercise can help improve body shape and regulate physical metabolic function in overweight or obese children.
Keywords：Overweight or obeseIntermittent hypoxiaAerobic exerciseBlood lipidsSerum uric acid
Publication Date：2026-06-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 906-910 )