Research progress on plant models of pulsed electric field catheter ablation
Li Yixuan
Yin Jiewen
Shao Wenyu
Jiang Chenxi
Abstract：Pulsed field ablation(PFA)is a non-thermal catheter ablation technique based on irreversible electroporation.With its unique tissue selectivity and safety,PFA has become a research hotspot in the field of arrhythmia treatment.This technology induces irreversible perforation of myocardial cell membranes through high-frequency electric pulses,and achieves targeted myocardial ablation while avoiding damage to adjacent tissues by utilizing the difference in tolerance thresholds to pulsed electric fields between myocardial cells and other tissues(such as blood vessels,nerves,and esophagus).Systematically summarizing the research progress of PFA plant models is crucial for clarifying the biophysical mechanism of PFA,optimizing pulse parameters and ablation strate-gies,and preventing potential complications.This article reviews the research progress of PFA plant models,aiming to provide a theoretical basis for the clinical translation and application expansion of this technology.
Keywords：Pulsed electric fieldCatheter ablationIrreversible electroporationPlant models
Publication Date：2026-05-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 778-780 )