Advances in the application of the"lung-gut axis"in traditional Chinese medicine treatment of chronic obstructive pulmonary disease based on the theory of"simultaneous treatment of lung and intestine"
Zhong Jiahui
Zhang Zhen
Yi Mingyang
Pang Ting
Zhou Wenjing
Song Dongmin
Wang Zhiwan
Abstract：Chronic obstructive pulmonary disease(COPD)is a highly prevalent respiratory disease world-wide,and its treatment is faced with challenges such as a long course of disease and recurrent attacks.In recent years,improving the clinical efficacy of COPD patients by regulating intestinal function has become a research hotspot.As one of the traditional Chinese medicine(TCM)Zang-Fu organ theories,"the lung and large intestine are interior-exterior related"proposes a unique idea of"simultaneous treatment of lung and intestine".Modern medicine has put forward the"lung-gut axis"theory based on the crosstalk relationship between microorganisms and their metabolites between the lung and large intestine,which provides a scientific basis and research direction for the TCM treatment of COPD.Based on the theory of"simultaneous treatment of lung and intestine"and with the modern research on the"lung-gut axis"as the key,this paper intends to systematically sort out the application progress from"simultaneous treatment of lung and intestine"to the"lung-gut axis".It expounds the treatment of COPD by TCM compound prescriptions,TCM enema,acupoint application and other methods,which can regulate intestinal flora imbalance,restore immune balance and exert a synergistic therapeutic effect.This study aims to give full play to the advantages of classic TCM theories in the research field of respiratory diseases and provide new ideas for the TCM treatment of COPD.
Keywords：Simultaneous treatment of lung and intestineLung-gut axisChronic obstructive pulmonary disease
Publication Date：2026-04-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 607-611 )