Application of the multidrug-resistant organism early warning assessment scale in the prevention and control of nosocomial infections in intensive care unit patients
Liang Xuefei
Zhang Xiaoxuan
Guo Liheng
He Jianzhuo
Chen Minggui
Yang Shuai
Wang Fangfang
Li Xinglong
Wu Qingjiao
Abstract：Objective To investigate the application effect of the multidrug-resistant organism(MDRO)early warning assessment scale in newly admitted patients to the intensive care unit(ICU).Methods A prospective observational study was conducted on 110 patients admitted to the Department of Critical Care Medicine,Guangdong Provincial Hospital of Traditional Chinese Medicine from August 2021 to February 2025,using a risk assessment scale containing five core indicators:patient source,length of hospital stay,age,duration of indwelling catheter,and high-risk factors.Receiver operating characteristic curve analysis was used to determine the optimal cut-off value of the assessment scale.Based on the principle of maximizing the Youden index,the optimal critical value was determined to be 9(the area under the curve was 0.78).Patients were divided into the high-risk group(≥9)and the low-risk group(≤8)according to the scores,and the difference in the MDRO detection rate between the two groups was compared.Results The MDRO detection rate in the high-risk group was significantly higher than that in the low-risk group[76.2％(32/42)vs 35.3％(24/68)](P＜0.001).A total of 194 pathogenic strains were isolated from all patients,among which 89 were MDRO strains(45.9％).The top four detected strains were Klebsiella pneumoniae(22 strains),Escherichia coli(15 strains),Staphylococcus aureus(12 strains)and Acinetobacter baumannii(12 strains).The rate of mixed infection was 30.9％(34/110).Conclusion The MDRO early warning assessment scale can effectively identify the high-risk population of MDRO among newly admitted ICU patients,and the implementation of pre-isolation measures for patients with a score of ≥9 points has important clinical value.
Keywords：Multidrug-resistant organismEarly warning assessmentIntensive care unitNosocomial infectionsPrevention and control strategies
Publication Date：2026-04-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 538-542 )