Clinical study on prognostic evaluation of low triiodothyronine syndrome and acute physiology and chronic health evaluation score in patients with Klebsiella pneumoniae pneumonia
Zhao Haiyang
Wang Miaomiao
Ma Shuai
Mei Xue
Abstract：Objective To investigate the predictive value of low triiodothyronine(T3)syndrome(LT3S)and acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ)score for the prognosis of patients with Klebsiella pneumoniae pneumonia.Methods The medical records of 63 patients with Klebsiella pneumoniae pneumonia admitted to Beijing Chao-Yang Hospital,Capital Medical University from January 2020 to December 2024 were retrospectively analyzed.The patients were divided into the survival group(26 cases)and the death group(37 cases)according to 30 d survival status.The clinical indicators were compared between the LT3S group(44 cases)and the normal T3 group(19 cases).The area under the receiver operating characteristic(ROC)curve(AUC)and Logistic regression analysis were used to evaluate the predictive value of LT3S and APACHE Ⅱscore for the prognosis of patients with Klebsiella pneumoniae pneumonia.Results The incidence of LT3 S in the death group was higher than that in the survival group[83.8％(31/37)vs 50.0％(13/26)](P=0.004).Logistic regression analysis showed that LT3 S and APACHE Ⅱ score were independent risk factors for 30 d death in patients with Klebsiella pneumoniae pneumonia(both P＜0.05).ROC curve analysis showed that the AUCs of T3 and APACHE Ⅱ score for predicting 30 d death were 0.930 and 0.858,respectively(P＞0.05).Conclusion The incidence of LT3S is high in patients with Klebsiella pneumoniae pneumonia.Both LT3S and APACHE Ⅱ score are independent risk factors for 30 d death in these patients,and there is no significant difference in their predictive efficacy.
Keywords：PneumoniaKlebsiella pneumoniaeLow triiodothyronine syndromeAcute physiology and chronic health evaluation Ⅱ
Publication Date：2026-03-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 358-361 )