Analysis of clinical characteristics of influenza B virus,adenovirus and respiratory syncytial virus infection in children

Wang Ziwei; Zhao Hehua

doi:10.3760/j.issn.1673-4777.2026.02.015

Abstract：Objective To analyze the different clinical characteristics and laboratory indicators of respiratory tract infections in children caused by influenza B,adenovirus,and respiratory syncytial virus.Methods A total of 668 children who visited the outpatient department or were hospitalized in Beijing Friendship Hospital,Capital Medical University from December 2023 to March 2024 were selected as the research subjects.According to the results of etiological nucleic acid detection,they were divided into influenza B group(259 cases),adenovirus group(216 cases),and respiratory syncytial virus group(193 cases).The clinical symptoms,laboratory indicators,and lymphocyte subset indicators of the three groups were compared.Results There were statistically significant differences in the proportions of moderate fever,high fever,sore throat,wheezing,vomiting,abdominal pain,headache,and concurrent Mycoplasma infection among the three groups(all P<0.05).There were statistically significant differences in white blood cell count,neutrophil count,lymphocyte count,monocyte count,and platelet count among the three groups(all P<0.05).There were statistically significant differences in CD+3,CD+8,CD+4,and CD+16 levels among the influenza B group,adenovirus group,and respiratory syncytial virus group[(1.86±0.25)vs(2.09±0.53),(2.14±0.46);(0.47±0.11)vs(1.02±0.26),(1.07±0.19);(1.25±0.38)vs(0.67±0.19),(1.18±0.35);(0.51±0.13)vs(0.54±0.07),(0.30±0.06)](all P<0.05).Conclusion After infection with the three viruses,children have common clinical manifestations and laboratory indicators of viral infection,as well as distinct manifestations and characteristics specific to each virus.