Research progress on the correlation between the imbalance of intestinal flora diversity and endometriosis
Zhang Qi
Liu Jiawei
Yu Congxiang
Suo Jing
Abstract：Endometriosis(EMs)is a common gynecological disease in which endometrial tissue(glands and stroma)occurs outside the body of the uterus.EMs has a wide range of lesions and benign morphology,but it cannot be denied that it has clinical behavior properties similar to malignant tumors such as adhesion,invasion and metastasis,and is prone to recurrence,which seriously affects the daily life and physical and mental health of female patients.So far,the specific pathogenesis of EMs has not been completely clear,but in recent years,more and more studies have shown that intestinal flora may be closely related to the occurrence and development of EMs.The effect of intestinal flora diversity imbalance on EMs may be related to the mechanism of participating in immune response,affecting the release of inflammatory factors,and participating in estrogen metabolism.EMs can be improved by regulating intestinal flora,such as intestinal microbiota preparations,fecal microbiota transplantation,and diet regulation.This article reviews the correlation between intestinal flora and EMs,the possible pathogenic mechanism of intestinal flora on EMs,and the possible methods of treating EMs by regulating intestinal flora.
Keywords：EndometriosisIntestinal floraPathogenesis
Publication Date：2025-12-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1910-1914 )