Analysis of multiple difficulties in obesity management and overview of comprehensive intervention strategies
Zhang Huizhen
Li Yanhua
Abstract：In China,body mass index over 28 kg/m2 is usually defined as obesity.Obesity is the fifth leading cause of death in the world,and its prevention and treatment effects directly affect the national health level.Recent studies have shown that metabolic adaptation is closely related to weight regain after weight loss in obese people.This article reviews the multiple difficulties and comprehensive intervention strategies in obesity management,such as metabolic adaptation,adipocyte memory effect,gene regulation,psychological factors,and environmental obesity-inducing effect,in order to provide reference for the prevention and treatment of obesity in the grassroots.
Keywords：ObesityMetabolic adaptationAdipocyte memoryPsychological factorsDietary regulationComprehensive intervention strategies
Publication Date：2025-12-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：6( 1896-1901 )