Difference analysis of bleeding risk and risk perception in elderly patients with atrial fibrillation receiving anticoagulant therapy in community

Shi Xiaoyi; Li Yanyan; Rao Jingjing; Li Li; Huang Jun

doi:10.3760/j.issn.1673-4777.2025.06.001

Abstract：Objective To investigate the current situation of differences in bleeding risk and risk perception in elderly patients with atrial fibrillation during anticoagulant therapy in the community,so as to provide reference for precise prevention of bleeding in patients.Methods A total of 487 elderly patients with atrial fibrillation who were accepted diagnosis and treatment guidance in Guangdong Provincial People's Hospital from June 2018 to July 2023 were selected as the research objects.The bleeding risk score and disease risk perception level at enrollment were investigated.Multiple linear regression method was used to analyze the influencing factors of bleeding risk and disease risk perception in elderly patients with atrial fibrillation receiving anticoagulant therapy in the community.Results Multivariate linear regression analysis showed that age,etiology of atrial fibrillation and medication were independent influencing factors for bleeding risk of community anticoagulant therapy in elderly patients with atrial fibrillation(standardized regression coefficients were 0.558,0.140,and 0.096,respectively,all P＜0.05).Age,family per capita monthly income,medication,comorbidity of hypertension and comorbidity of hyperglycemia were independent influencing factors of disease risk perception of community anticoagulation therapy in elderly patients with atrial fibrillation(standardized regression coefficients were 0.341,-0.482,0.064,0.059,and 0.100,respectively,all P＜0.05).Conclusion Elderly patients with atrial fibrillation have a high risk of bleeding during anticoagulant therapy in the community,and there is a bias in disease risk perception.The patients are affected by age,medication and comorbidities,which increase the risk of bleeding and reduce the ability of disease risk perception.