Clinical study of Jianpi Wenyang decoction in the treatment of epigastric pain syndrome of spleen and stomach weakness in grassroots training participants

Cui Yixin; Wang Decai; Xie Dongqing; Wang Haiming; Zhang Yin; Wang Yujia; Li Shaodan

doi:10.3760/j.issn.1673-4777.2025.05.023

Abstract：Objective To investigate the clinical effect of Jianpi Wenyang decoction in the treatment of epigastric pain syndrome(EPS)of spleen and stomach weakness in grassroots training participants.Methods A total of 84 patients with functional dyspepsia of spleen and stomach weakness admitted to the First Medical Center of Chinese PLA General Hospital from February to August 2023 were selected as the research objects.According to the random number table method,they were divided into the control group(42 cases)and the observation group(42 cases).The control group was treated with omeprazole magnesium enteric-coated tablets on the basis of basic treatment,and the observation group was treated with external application of Jianpi Wenyang decoction on the basis of basic treatment.The gastrointestinal symptom scores,gastric motor function,traditional Chinese medicine syndrome scores,efficacy and safety were compared between the two groups.Results During the experiment,2 cases of control group dropout occurred.After treatment,the gastrointestinal symptom scores of the two groups were significantly lower than those before treatment,and the scores of postprandial fullness and early satietythe in the observation group were lower than those in the control group(all P＜0.05).After treatment,the antral contraction amplitude,antral contraction frequency and antral motility index of the two groups were higher than those before treatment,and the antral motility index of the observation group was higher than that of the control group(all P＜0.05).After treatment,the traditional Chinese medicine syndrome scores of the two groups were lower than those before treatment,and the traditional Chinese medicine syndrome scores of poor appetite,fatigue,and aggravation after eating in the observation group were lower than those in the control group(all P＜0.05).The total effective rate of the observation group was higher than that of the control group[95.2％(40/42)vs 72.5％(29/40)(x2=7.940,P=0.005).During the treatment,no adverse reactions occurred in the two groups.Conclusion Jianpi Wenyang decoction can not only significantly improve the clinical symptoms of EPS such as abdominal distension and early satiety,but also relieve the accompanying symptoms such as fatigue and poor appetite,so as to improve the quality of life of the training participants.